...Until now, antibody tests have been typically looked for evidence of a range of antibody types, including generally fast-appearing but short-lived ones and another kind that shows up later but provides longer protection.
Healthineers’ new test zeroes in on the latter. Once an organization like the International Federation of Clinical Chemistry and Laboratory Medicine determines what level of these antibodies is needed to confer immunity, researchers will be able to see who needs a vaccine, a booster shot or nothing at all.
...T cells can kill virus-infected cells, while memory cells linger for years, ready to re-populate the body with both weapons if the virus returns.
..presence of antibodies targeting the nucleocapsid that surrounds the coronavirus’s nucleic acids.
However, research has shown that the most protective antibodies are those that target the spike protein that enables the virus to enter cells. Most vaccine developers are coming up with shots inducing the body to make spike protein-related antibodies,
...Roche’s quantitative test focuses on spike-protein antibodies. The company will then be able to use both of its antibody tests together, a potential benefit since a small percentage of people develop antibodies against either the spike or the nucleocapsid, not both.
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